oxidative stress statues in serum and follicular fluid of women with endometriosis
نویسندگان
چکیده
objective: this study aimed to evaluate the levels of two oxidative stress (os) markers including lipid peroxide (lpo) and total antioxidant capacity (tac) in both serum and follicular fluid (ff) of women with endometriosis after puncture. materials and methods: in this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endometriosis diagnosis) indication underwent in vitro fertilization (ivf) program in the royan institute, tehran, iran from september 2013 to october 2014. about forty-three patients were diagnosed with endometriosis after laparoscopy. blood and ff from the leading follicle in each stimulated ovary were obtained at the time of egg retrieval; samples were centrifuged and frozen until assessment. at the time of sample assessment, serum and ff samples were evaluated for the levels of lpo and tac on spectrophotometery. results: we observed that women with endometriosis had significantly higher lpo and lower tac levels in the serum and ff as compared with the control group (p<0.05). conclusion: it has observed that ff of women with endometriosis, regardless of disease stage, increases the proliferation power of endometrial cells in vitro, we presume that inflammatory reactions-induced os in ovary may be responsible for proliferation induction ability in ff obtained from women with endometriosis.
منابع مشابه
Oxidative Stress Statues in Serum and Follicular Fluid of Women with Endometriosis
OBJECTIVE This study aimed to evaluate the levels of two oxidative stress (OS) markers including lipid peroxide (LPO) and total antioxidant capacity (TAC) in both serum and follicular fluid (FF) of women with endometriosis after puncture. MATERIALS AND METHODS In this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endom...
متن کامل[Serum markers of oxidative stress in infertile women with endometriosis].
PURPOSE to compare serum markers of oxidative stress between infertile patients with and without endometriosis and to assess the association of these markers with disease staging. METHODS this was a prospective study conducted on 112 consecutive infertile, non-obese patients younger than 39 years, divided into two groups: Endometriosis (n=48, 26 with minimal and mild endometriosis - Stage I/I...
متن کاملSerum and Peritoneal Fluid Levels of Vascular Endothelial Growth Factor in Women with Endometriosis
متن کامل
Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis
Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T cell subsets participate in the establishment and progress of the disease by producing different cytokines. Objective: To investigate a group of cytokines related to Th1/Th2/Th17/Treg subsets within both peripheral blood...
متن کاملSerum and Peritoneal Fluid CA 125 Levels Infertile Women with Pelvic Endometriosis in Urummia
SUMMARY Infertility has a special importance in gynecology in causing social, psychological and somatic prohlems. Endometriosis is a benign but progressive disorder in reproductive life and is more common in infertile women. CA 125 is a cell membrane glycoprotein. The endometrium is one the known source of this antigen and seems to be elevated in the pelvic endometriosis. In this study, from...
متن کاملThe Correlation between Serum and Peritoneal Fluid CA125 Level in Women with Pelvic Endometriosis
Background Despite a high prevalence of endometriosis, there still exist many challenges in diagnosing the disease. This study aims to evaluate non-invasive and practical diagnostic methods by measuring serum and peritoneal fluid CA 125 levels in patients with endometriosis. A secondary aim is to determine the correlation between these markers with the stage of disease as well as the relationsh...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
cell journalجلد ۱۸، شماره ۴، صفحات ۵۸۲-۵۸۷
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023